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Anti-FANCC Antibody

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ABclonal
A1812
Overview
Name: Anti-FANCC Antibody
Description: Rabbit polyclonal antibody to FANCC.
Applications: WB, IHC, IF
Dilutions: WB 1:500 - 1:2000, IHC 1:50 - 1:200, IF 1:50 - 1:200
Reactivity: Human
Immunogen: Recombinant protein of human FANCC
Protein Length: 558
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at -20℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.
Tissue Specificity: Ubiquitous.
Involvement in Disease: Fanconi anemia complementation group C: A disorder affecting all bone marrow elements and resulting in anemia, leukopenia and thrombopenia. It is associated with cardiac, renal and limb malformations, dermal pigmentary changes, and a predisposition to the development of malignancies. At the cellular level it is associated with hypersensitivity to DNA-damaging agents, chromosomal instability (increased chromosome breakage) and defective DNA repair.
Cellular Location: Nucleus. Cytoplasm.

The major form is nuclear. The minor form is cytoplasmic.
UniProt: Q00597
Gene ID: 2176
Synonyms: bA80I15.1 Antibody
FA 3 Antibody
FA3 Antibody
FAC Antibody
FACC Antibody
FANCC_HUMAN Antibody
Fanconi anemia complementation group C Antibody
Fanconi anemia complementation group C protein Antibody
Fanconi anemia group C protein Antibody
Fanconi pancytopenia type 3 Antibody
FLJ14675 Antibody
Protein FACC Antibody

Images
Western Blot - Anti-FANCC Antibody from ABclonal (A1812) - Antibody Supply Service
Western blot analysis of extracts of various cell lines, using FANCC antibody.
Immunofluorescence - Anti-FANCC Antibody from ABclonal (A1812) - Antibody Supply Service
Immunofluorescence analysis of U2OS cell using FANCC antibody. Blue: DAPI for nuclear staining.

Product Code - A1812
Size Price Quantity
50µl £148
100µl £243
200µl £372

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