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Anti-MDM4 Antibody

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ABclonal
A1747
Overview
Name: Anti-MDM4 Antibody
Description: Rabbit polyclonal antibody to MDM4.
Applications: WB
Dilutions: WB 1:500 - 1:1000
Reactivity: Human
Immunogen: A synthetic Peptide of human MDM4
Protein Length: 490
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at 4℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions.
Tissue Specificity: Expressed in all tissues tested with high levels in thymus.
Sequence Similarities: Belongs to the MDM2/MDM4 family.
Post-Translational Modification: Phosphorylated. Phosphorylation at Ser-367 promotes interaction with YWHAG and subsequent ubiquitination and degradation. Phosphorylation at Ser-342 also induces ubiquitination and degradation but to a lower extent.
Cellular Location: Nucleus.
UniProt: O15151
Gene ID: 4194
Synonyms: DKFZp781B1423 Antibody
Double minute 4 Antibody
Double minute 4 human homolog of p53 binding protein Antibody
Double minute 4 protein Antibody
HDMX Antibody
MDM 4 Antibody
Mdm2 like p53 binding protein Antibody
Mdm2-like p53-binding protein Antibody
Mdm4 p53 binding protein homolog mouse Antibody
Mdm4 protein Antibody
MDM4 related protein 1 Antibody
Mdm4 transformed 3T3 cell double minute 4 Antibody
Mdm4 transformed 3T3 cell double minute 4 p53 binding protein Antibody
Mdm4 transformed 3T3 cell double minute 4 p53 binding protein mouse Antibody
MDM4_HUMAN Antibody
MDMX Antibody
MDMX (phospho S367) Antibody
MDMX (phospho S403) Antibody
Mdmx protein Antibody
MGC132766 Antibody
Mouse double minute 4 homolog Antibody
Mouse double minute 4 human homolog of p53 binding protein Antibody
MRP 1 Antibody
MRP1 Antibody
p53 binding protein Antibody
p53 BINDING PROTEIN MDM4 Antibody
p53-binding protein Mdm4 Antibody
Protein Mdm4 Antibody
Protein Mdmx Antibody

Images
Western Blot - Anti-MDM4 Antibody from ABclonal (A1747) - Antibody Supply Service
Western blot analysis of extracts of ZR-75-1 cells, using MDM4 antibody.

Product Code - A1747
Size Price Quantity
100µl £243
200µl £372

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