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Anti-SELPLG Antibody

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ABclonal
A1660
Overview
Name: Anti-SELPLG Antibody
Description: Rabbit polyclonal antibody to SELPLG.
Applications: WB, IHC, IF
Dilutions: WB 1:500 - 1:2000, IHC 1:50 - 1:200, IF 1:50 - 1:200
Reactivity: Human
Immunogen: Recombinant protein of human SELPLG
Protein Length: 412
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at -20℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: A SLe(x)-type proteoglycan, which through high affinity, calcium-dependent interactions with E-, P- and L-selectins, mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation. Critical for the initial leukocyte capture.
Tissue Specificity: Expressed on neutrophils, monocytes and most lymphocytes.
Post-Translational Modification: Displays complex, core-2, sialylated and fucosylated O-linked oligosaccharides, at least some of which appear to contain poly-N-acetyllactosamine with varying degrees of substitution. Mainly disialylated or neutral forms of the core-2 tetrasaccharide, Galbeta1-->4GlcNAcbeta1-->6(Galbeta1-->3)GalNAcOH. The GlcN:GalN ratio is approximately 2:1 and the Man:Fuc ratio 3:5. Contains about 14% fucose with alpha-1,3 linkage present in two forms: One species is a disialylated, monofucosylated glycan, and the other, a monosialylated, trifucosylated glycan with a polylactosamine backbone. The fucosylated forms carry the Lewis antigen and are important for interaction with selectins and for functioning in leukocyte rolling. The modification containing the sialyl Lewis X glycan is on Thr-57. No sulfated O-glycans. Some N-glycosylation.
Cellular Location: Membrane.
UniProt: Q14242
Gene ID: 6404
Synonyms: CD 162 Antibody
CD162 Antibody
CD162 antigen Antibody
CLA Antibody
Cutaneous lymphocyte associated associated antigen Antibody
P selectin glycoprotein ligand 1 Antibody
P selectin glycoprotein ligand 1 precursor Antibody
P-selectin glycoprotein ligand 1 Antibody
PSGL 1 Antibody
PSGL-1 Antibody
PSGL1 Antibody
Selectin P ligand Antibody
SELPL_HUMAN Antibody

Images
Western Blot - Anti-SELPLG Antibody from ABclonal (A1660) - Antibody Supply Service
Western blot analysis of extracts of various cell lines, using SELPLG antibody.
Immunofluorescence - Anti-SELPLG Antibody from ABclonal (A1660) - Antibody Supply Service
Immunofluorescence analysis of HeLa cell using SELPLG antibody.

Product Code - A1660
Size Price Quantity
50µl £148
100µl £243
200µl £372

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