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Anti-IFNB1 Antibody

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ABclonal
A1575
Details
Description: Rabbit polyclonal antibody to IFNB1.
Category: Primary Antibodies
Applications: WB, IHC, IF
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Reactivity: Human
UniProt: P01574
Gene ID: 3456
Immunogen: Recombinant protein of human IFNB1
Protein Length: 187
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonyms: IFNB1; IFB; IFF; IFNB; MGC96956
Purification: Affinity purification
Background: The genes encoding type I interferons (IFNs), which include 14 IFN-? genes, one IFN-∫ gene, one IFN-w (also known as IFN-? II1) gene, and a number of IFN-w pseudogenes, are clustered on human chromosome 9. Interferons-? and -∫ are cytokines that are widely known to induce potent antiviral activity. IFN-? and -∫ exert a variety of other biological effects, including antitumor and immunomodulatory activities and are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. IFN-w is antigenically different from human IFN-?, IFN-∫ or IFN-?, but is a component of natural mixtures of IFN species produced by virus-induced leukocytes or Burkitt's lymphoma cells. The type I interferon receptor (IFN-?R) interacts with IFN-?, IFN-∫ and IFN-w, and seems to be a multisubunit receptor.
Storage: Store at -20℃. Avoid freeze / thaw cycles.
Recommended Dilutions: WB 1:500 - 1:2000, IHC 1:50 - 1:200, IF 1:50 - 1:200

Target (Information from UniProt)
Function: Has antiviral, antibacterial and anticancer activities.
Sequence Similarities: Belongs to the alpha/beta interferon family.
Cellular Location: Secreted.

Images
Western Blot - Anti-IFNB1 Antibody from ABclonal (A1575) - Antibody Supply Service
Western blot analysis of extracts of various cell lines, using IFNB1 antibody.
Immunohistochemistry - Anti-IFNB1 Antibody from ABclonal (A1575) - Antibody Supply Service
Immunohistochemistry of paraffin-embedded human kidney using IFNB1 antibody at dilution of 1:200 (x400 lens)
Immunohistochemistry - Anti-IFNB1 Antibody from ABclonal (A1575) - Antibody Supply Service
Immunohistochemistry of paraffin-embedded human esophageal cancer using IFNB1 antibody at dilution of 1:200 (x400 lens)
Immunofluorescence - Anti-IFNB1 Antibody from ABclonal (A1575) - Antibody Supply Service
Immunofluorescence analysis of HepG2 cell using IFNB1 antibody. Blue: DAPI for nuclear staining.

Product Code - A1575
Size Price Quantity
50µl £148
100µl £243
200µl £372

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