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Anti-USP1 Antibody

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ABclonal
A1473
Overview
Name: Anti-USP1 Antibody
Description: Rabbit polyclonal antibody to USP1.
Applications: WB
Dilutions: WB 1:200 - 1:2000
Reactivity: Human
Immunogen: A synthetic peptide of human USP1
Protein Length: 785
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at 4℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: Negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2 (PubMed:15694335). Also involved in PCNA-mediated translesion synthesis (TLS) by deubiquitinating monoubiquitinated PCNA (PubMed:16531995). Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity (PubMed:18082604, PubMed:26388029).
Sequence Similarities: Belongs to the peptidase C19 family.
Post-Translational Modification: Autocatalytic cleavage of USP1 following UV irradiation inactivates it leading to an increase in ubiquitinated PCNA, recruitment of POLH and translesion synthesis.
Cellular Location: Nucleus.
UniProt: O94782
Gene ID: 7398
Synonyms: Deubiquitinating enzyme 1 Antibody
hUBP Antibody
Ubiquitin carboxyl terminal hydrolase 1 Antibody
Ubiquitin carboxyl-terminal hydrolase 1 Antibody
Ubiquitin specific peptidase 1 Antibody
Ubiquitin specific protease 1 Antibody
Ubiquitin thioesterase 1 Antibody
Ubiquitin thiolesterase 1 Antibody
Ubiquitin-specific-processing protease 1 Antibody
UBP Antibody
UBP1_HUMAN Antibody
USP 1 Antibody

Images
Western Blot - Anti-USP1 Antibody from ABclonal (A1473) - Antibody Supply Service
Western blot analysis of 293 cell and HeLa cell lysate using USP1 antibody.

Product Code - A1473
Size Price Quantity
100µl £243
200µl £372

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