phone icon
+44 (0)1223 298875

Anti-APOA5 Antibody

file icon Datasheet
ABclonal
A1424
Overview
Name: Anti-APOA5 Antibody
Description: Rabbit polyclonal antibody to APOA5.
Applications: WB, IHC
Dilutions: WB 1:500 - 1:2000, IHC 1:50 - 1:100
Reactivity: Human
Immunogen: Recombinant protein of human APOA5
Protein Length: 366
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at -20℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: Minor apolipoprotein mainly associated with HDL and to a lesser extent with VLDL. May also be associated with chylomicrons. Important determinant of plasma triglyceride (TG) levels by both being a potent stimulator of apo-CII lipoprotein lipase (LPL) TG hydrolysis and a inhibitor of the hepatic VLDL-TG production rate (without affecting the VLDL-apoB production rate) (By similarity). Activates poorly lecithin:cholesterol acyltransferase (LCAT) and does not enhance efflux of cholesterol from macrophages.
Tissue Specificity: Liver and plasma.
Involvement in Disease: Hypertriglyceridemia, familial: A common inherited disorder in which the concentration of very low density lipoprotein (VLDL) is elevated in the plasma. This leads to increased risk of heart disease, obesity, and pancreatitis.

Hyperlipoproteinemia 5: Characterized by increased amounts of chylomicrons and very low density lipoprotein (VLDL) and decreased low density lipoprotein (LDL) and high density lipoprotein (HDL) in the plasma after a fast. Numerous conditions cause this phenotype, including insulin-dependent diabetes mellitus, contraceptive steroids, alcohol abuse, and glycogen storage disease type 1A (GSD1A).
Sequence Similarities: Belongs to the apolipoprotein A1/A4/E family.
Post-Translational Modification: Phosphorylated by FAM20C in the extracellular medium.
Cellular Location: Secreted.
UniProt: Q6Q788
Gene ID: 116519
Synonyms: Apo-AV Antibody
ApoA-V Antibody
APOA5_HUMAN Antibody
ApoAV Antibody
Apolipoprotein A V Antibody
Apolipoprotein A-V Antibody
Apolipoprotein A5 Antibody
RAP3 Antibody
Regeneration associated protein 3 Antibody
Regeneration-associated protein 3 Antibody

Images
Western Blot - Anti-APOA5 Antibody from ABclonal (A1424) - Antibody Supply Service
Western blot analysis of extracts of Recombinant protein, using APOA5 antibody.
Immunohistochemistry - Anti-APOA5 Antibody from ABclonal (A1424) - Antibody Supply Service
Immunohistochemistry of paraffin-embedded human liver using APOA5 antibody at dilution of 1:100 (40x lens).

Product Code - A1424
Size Price Quantity
50µl £148
100µl £243
200µl £372

or
Request a quotation
Contact us directly to order
  • call icon +44 (0)1223 298875
  • +44 (0)1223 281447
  • email icon orders@ab-y-ss.com
Product Quality
  • guarantee icon
  • We promise guaranteed product quality
  • and expert customer service.
Shipping Information
  • £20 to United Kingdom
  • £35 to Europe