|Description:||Mouse monoclonal antibody to IGF2.|
|Dilutions:||WB 1:500 - 1:2000|
|Immunogen:||A synthetic Peptide of human IGF2|
|Formulation:||PBS with 0.02% sodium azide, 50% glycerol, pH7.3.|
|Storage:||Store at 4℃. Avoid freeze / thaw cycles.|
Target (Information from UniProt)
|Function:||The insulin-like growth factors possess growth-promoting activity. In vitro, they are potent mitogens for cultured cells. IGF-II is influenced by placental lactogen and may play a role in fetal development.|
|Involvement in Disease:||Silver-Russell syndrome: A clinically heterogeneous condition characterized by severe intrauterine growth retardation, poor postnatal growth, craniofacial features such as a triangular shaped face and a broad forehead, body asymmetry, and a variety of minor malformations. The phenotypic expression changes during childhood and adolescence, with the facial features and asymmetry usually becoming more subtle with age.
Growth restriction, severe, with distinctive facies: A disease characterized by severe prenatal and postnatal growth restriction, facial dysmorphism, and short stature in the presence of normal or slightly elevated growth hormone levels.
|Sequence Similarities:||Belongs to the insulin family.|
|Post-Translational Modification:||O-glycosylated with core 1 or possibly core 8 glycans. Thr-96 is a minor glycosylation site compared to Thr-99.|
IGF 2 Antibody
IGF II Antibody
Insulin like Growth Factor 2 Antibody
insulin like growth factor 2 (somatomedin A) Antibody
Insulin like growth factor II Antibody
Insulin like growth factor II precursor Antibody
Insulin like growth factor type 2 Antibody
putative insulin like growth factor II associated protein Antibody
Somatomedin A Antibody
T3M 11 derived growth factor Antibody
Western blot analysis of extracts of various cell lines, using IGF2 antibody.