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Anti-ABCG2 Antibody

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ABclonal
A1370
Overview
Name: Anti-ABCG2 Antibody
Description: Rabbit polyclonal antibody to ABCG2.
Applications: WB, IHC, FC
Dilutions: WB 1:500 - 1:1000, IHC 1:20 - 1:50, FC 1:20 - 1:50
Reactivity: Human
Immunogen: A synthetic Peptide of human ABCG2
Protein Length: 655
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at 4℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: High-capacity urate exporter functioning in both renal and extrarenal urate excretion. Plays a role in porphyrin homeostasis as it is able to mediates the export of protoporhyrin IX (PPIX) both from mitochondria to cytosol and from cytosol to extracellular space, and cellular export of hemin, and heme. Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. Implicated in the efflux of numerous drugs and xenobiotics: mitoxantrone, the photosensitizer pheophorbide, camptothecin, methotrexate, azidothymidine (AZT), and the anthracyclines daunorubicin and doxorubicin.
Tissue Specificity: Highly expressed in placenta. Low expression in small intestine, liver and colon.
Sequence Similarities: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
Post-Translational Modification: Glycosylation-deficient ABCG2 is normally expressed and functional.
Cellular Location: Cell membrane. Mitochondrion membrane.
UniProt: Q9UNQ0
Gene ID: 9429
Synonyms: ABC transporter Antibody
ABC15 Antibody
ABCG 2 Antibody
ABCG2_HUMAN Antibody
ABCP Antibody
ATP binding cassette sub family G (WHITE) member 2 Antibody
ATP binding cassette transporter G2 Antibody
ATP-binding cassette sub-family G member 2 Antibody
BCRP Antibody
BCRP/ABCG2 Antibody
BCRP1 Antibody
BMDP Antibody
Breast cancer resistance protein Antibody
CD338 Antibody
CDw338 Antibody
CDw338 antigen Antibody
EST157481 Antibody
GOUT1 Antibody
MGC102821 Antibody
Mitoxantrone resistance associated protein Antibody
Mitoxantrone resistance-associated protein Antibody
MRX Antibody
Multi drug resistance efflux transport ATP binding cassette sub family G (WHITE) member 2 Antibody
MXR Antibody
MXR1 Antibody
Placenta specific ATP binding cassette transporter Antibody
Placenta specific MDR protein Antibody
Placenta-specific ATP-binding cassette transporter Antibody
UAQTL1 Antibody

Images
Western Blot - Anti-ABCG2 Antibody from ABclonal (A1370) - Antibody Supply Service
Western blot analysis of extracts of various cell lines, using ABCG2 antibody.

Product Code - A1370
Size Price Quantity
100µl £243
200µl £372

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