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Anti-APOB Antibody

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ABclonal
A1329
Overview
Name: Anti-APOB Antibody
Description: Mouse monoclonal antibody to APOB.
Applications: WB, ICC, FC
Dilutions: WB 1:500 - 1:2000, ICC 1:500 - 1:1000, FC 1:50 - 1:200
Reactivity: Human
Immunogen: Recombinant protein of human APOB
Protein Length: 4563
Host: Mouse
Clonality: Monoclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at 4℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor.
Involvement in Disease: Hypobetalipoproteinemia, familial, 1: A disorder of lipid metabolism characterized by less than 5th percentile age- and sex-specific levels of low density lipoproteins, and dietary fat malabsorption. Clinical presentation may vary from no symptoms to severe gastrointestinal and neurological dysfunction similar to abetalipoproteinemia.

Familial ligand-defective apolipoprotein B-100: Dominantly inherited disorder of lipoprotein metabolism leading to hypercholesterolemia and increased proneness to coronary artery disease (CAD). The plasma cholesterol levels are dramatically elevated due to impaired clearance of LDL particles by defective APOB/E receptors.
Post-Translational Modification: Palmitoylated; structural requirement for proper assembly of the hydrophobic core of the lipoprotein particle.
Cellular Location: Cytoplasm. Secreted.
UniProt: P04114
Gene ID: 338
Synonyms: apo b-100 Antibody
Apo B-48 Antibody
ApoB 100 Antibody
ApoB 48 Antibody
apoB-48R Antibody
APOB48R Antibody
APOBR Antibody
APOBR_HUMAN Antibody
APOB_HUMAN Antibody
Apolipoprotein B Antibody
Apolipoprotein B 100 Antibody
Apolipoprotein B receptor Antibody
Apolipoprotein B-100 receptor Antibody
Apolipoprotein B-48 Antibody
Apolipoprotein B-48 receptor Antibody
Apolipoprotein B48 Antibody
Apolipoprotein B48 receptor Antibody
FLDB Antibody
LDLCQ4 Antibody

Images
Western Blot - Anti-APOB Antibody from ABclonal (A1329) - Antibody Supply Service
Western blot analysis of extracts of Recombinant protein, using APOB antibody.

Product Code - A1329
Size Price Quantity
50µl £199
100µl £307
200µl £452

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