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Anti-HLA-B Antibody

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Description: Rabbit polyclonal antibody to HLA-B.
Category: Primary Antibodies
Applications: WB
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Reactivity: Human
UniProt: P01889
Gene ID: 3106
Immunogen: A synthetic peptide of human HLA-B
Protein Length: 362
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonyms: AS; HLA-B-7301; HLA-B73; HLAB; HLAC; MGC111087; SPDA1
Purification: Affinity purification
Background: Human major histocompatibility complex (MHC) antigens, also referred to as human leukocyte antigens (HLA), are encoded by genes located on the short arm of chromosome 6 (6p21.3). There are two classes of HLA antigens: class I (HLA-A, B and C) and class II (HLA-D). This class I molecules are polymorphic membrane glycoproteins composed of a heavy (alpha) chain (44 kDa) which is encoded by a HLA class I gene (HLA-A, B or C), and β2-microglobulin light (beta) chain (12 kDa). They are involved in the presentation of foreign antigens to the immune system. (PMID: 667938; 3375250)
Storage: Store at 4℃. Avoid freeze / thaw cycles.
Recommended Dilutions: WB 1:1000 - 1:2000

Target (Information from UniProt)
Function: Involved in the presentation of foreign antigens to the immune system.
Sequence Similarities: Belongs to the MHC class I family.
Post-Translational Modification: Polyubiquitinated in a post ER compartment by interaction with human herpesvirus 8 MIR1 protein. This targets the protein for rapid degradation via the ubiquitin system (By similarity).
Cellular Location: Membrane.

Western Blot - Anti-HLA-B Antibody from ABclonal (A1285) - Antibody Supply Service
Western blot analysis of extracts of Jurkat cell line, using HLA-B antibody.

Product Code - A1285
Size Price Quantity
100µl £243
200µl £372

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