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Anti-SENP1 Antibody

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ABclonal
A1260
Overview
Name: Anti-SENP1 Antibody
Description: Rabbit polyclonal antibody to SENP1.
Applications: WB, IHC
Dilutions: WB 1:1000 - 1:2000, IHC 1:50 - 1:200
Reactivity: Human
Immunogen: A synthetic peptide of human SENP1
Protein Length: 644
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at -20℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. Deconjugates SUMO1 from HIPK2. Deconjugates SUMO1 from HDAC1 and BHLHE40/DEC1, which decreases its transcriptional repression activity. Deconjugates SUMO1 from CLOCK, which decreases its transcriptional activation activity. Deconjugates SUMO2 from MTA1. Desumoylates CCAR2 which decreases its interaction with SIRT1 (PubMed:25406032).
Tissue Specificity: Highly expressed in testis. Expressed at lower levels in thymus, pancreas, spleen, liver, ovary and small intestine.
Sequence Similarities: Belongs to the peptidase C48 family.
Cellular Location: Nucleus. Cytoplasm.

Shuttles between cytoplasm and nucleus.
UniProt: Q9P0U3
Gene ID: 29843
Synonyms: SENP 1 Antibody
SENP1_HUMAN Antibody
Sentrin specific protease 1 Antibody
Sentrin-specific protease 1 Antibody
Sentrin/SUMO specific protease Antibody
Sentrin/SUMO specific protease 1 Antibody
Sentrin/SUMO specific protease SENP 1 Antibody
Sentrin/SUMO specific protease SENP1 Antibody
Sentrin/SUMO-specific protease SENP1 Antibody
SUMO1/sentrin specific peptidase 1 Antibody
SUMO1/sentrin specific protease 1 Antibody
SuPr 2 Antibody
SuPr2 Antibody

Images
Western Blot - Anti-SENP1 Antibody from ABclonal (A1260) - Antibody Supply Service
Western blot analysis of extracts of various cell lines, using SENP1 antibody.

Product Code - A1260
Size Price Quantity
100µl £243
200µl £372

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