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Anti-F11R Antibody

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ABclonal
A1241
Overview
Name: Anti-F11R Antibody
Description: Rabbit polyclonal antibody to F11R.
Applications: WB, IHC, IF
Dilutions: WB 1:500 - 1:2000, IHC 1:50 - 1:200, IF 1:50 - 1:200
Reactivity: Human
Immunogen: Recombinant protein of human F11R
Protein Length: 299
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at -20℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3 (PubMed:11489913). The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier (By similarity). Ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration (PubMed:11812992). Involved in platelet activation (PubMed:10753840).
Tissue Specificity: Expressed in endothelium, epithelium and leukocytes (at protein level).
Sequence Similarities: Belongs to the immunoglobulin superfamily.
Post-Translational Modification: N-glycosylated.
Cellular Location: Cell junction > Tight junction. Cell membrane.

Localized at tight junctions of both epithelial and endothelial cells.
UniProt: Q9Y624
Gene ID: 50848
Synonyms: CD 321 Antibody
CD321 Antibody
CD321 antigen Antibody
ESTM33 Antibody
F11 receptor Antibody
JAM Antibody
JAM 1 Antibody
JAM A Antibody
JAM-1 Antibody
JAM-A Antibody
JAM1 Antibody
JAM1_HUMAN Antibody
JAMA Antibody
JCAM Antibody
Jcam1 Antibody
Junction adhesion molecule 1 Antibody
Junction adhesion molecule, mouse, homolog of Antibody
Junctional Adhesion Molecule 1 Antibody
Junctional adhesion molecule A Antibody
KAT Antibody
Ly106 Antibody
PAM 1 Antibody
PAM-1 Antibody
PAM1 Antibody
Platelet adhesion molecule Antibody
Platelet adhesion molecule 1 Antibody
Platelet F11 receptor Antibody
PRO301 Antibody
UNQ264 Antibody

Images
Western Blot - Anti-F11R Antibody from ABclonal (A1241) - Antibody Supply Service
Western blot analysis of extracts of various cells, using F11R antibody.
Immunofluorescence - Anti-F11R Antibody from ABclonal (A1241) - Antibody Supply Service
Immunofluorescence analysis of HeLa cell using F11R antibody. Blue: DAPI for nuclear staining.

Product Code - A1241
Size Price Quantity
50µl £148
100µl £243
200µl £372

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