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Anti-TNFRSF10B Antibody

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ABclonal
A1236
Overview
Name: Anti-TNFRSF10B Antibody
Description: Rabbit polyclonal antibody to TNFRSF10B.
Applications: WB, IHC
Dilutions: WB 1:500 - 1:2000, IHC 1:50 - 1:200
Reactivity: Human
Immunogen: Recombinant protein of human TNFRSF10B
Protein Length: 440
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at -20℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis.
Tissue Specificity: Widely expressed in adult and fetal tissues; very highly expressed in tumor cell lines such as HeLaS3, K-562, HL-60, SW480, A-549 and G-361; highly expressed in heart, peripheral blood lymphocytes, liver, pancreas, spleen, thymus, prostate, ovary, uterus, placenta, testis, esophagus, stomach and throughout the intestinal tract; not detectable in brain.
Involvement in Disease: Squamous cell carcinoma of the head and neck: A non-melanoma skin cancer affecting the head and neck. The hallmark of cutaneous SCC is malignant transformation of normal epidermal keratinocytes.
Cellular Location: Membrane.
UniProt: O14763
Gene ID: 8795
Synonyms: Fas like protein Antibody
Apoptosis inducing protein TRICK2A 2B Antibody
Apoptosis inducing protein TRICK2A/2B Antibody
Apoptosis inducing receptor TRAIL R2 Antibody
CD262 Antibody
CD262 antigen Antibody
Cytotoxic TRAIL receptor 2 Antibody
Death domain containing receptor for TRAIL Apo 2L Antibody
Death domain containing receptor for TRAIL/Apo 2L Antibody
Death receptor 5 Antibody
DR5 Antibody
Fas like protein Antibody
KILLER Antibody
Killer DR5 Antibody
KILLER/DR5 Antibody
OTTHUMP00000123492 Antibody
OTTHUMP00000123493 Antibody
p53 regulated DNA damage inducible cell death receptor killer Antibody
p53 regulated DNA damage inducible cell death receptor(killer) Antibody
sTRAIL Receptor 2 Antibody
TNF receptor superfamily member 10b Antibody
TNF related apoptosis inducing ligand receptor 2 Antibody
TNF-related apoptosis-inducing ligand receptor 2 Antibody
TR10B_HUMAN Antibody
TRAIL R2 Antibody
TRAIL receptor 2 Antibody
TRAIL-R2 Antibody
TRAILR2 Antibody
TRICK2 Antibody
TRICK2A Antibody
TRICK2B Antibody
TRICKB Antibody
Tumor necrosis factor receptor like protein ZTNFR9 Antibody
Tumor necrosis factor receptor superfamily member 10B Antibody
Tumor necrosis factor receptor superfamily, member 10b Antibody
ZTNFR9 Antibody

Images
Western Blot - Anti-TNFRSF10B Antibody from ABclonal (A1236) - Antibody Supply Service
Western blot analysis of extracts of various cell lines, using TNFRSF10B antibody.

Product Code - A1236
Size Price Quantity
50µl £148
100µl £243
200µl £372

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