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Anti-KLK3 Antibody

file icon Datasheet
Description: Mouse monoclonal antibody to KLK3.
Category: Primary Antibodies
Applications: WB, IHC, FC
Host: Mouse
Clonality: Monoclonal
Isotype: IgG
Reactivity: Human
UniProt: P07288
Gene ID: 354
Immunogen: Recombinant protein of human KLK3
Protein Length: 261
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonyms: KLK3; APS; KLK2A1; PSA; hK3; Prostate-specific antigen; KLK3
Purification: Affinity purification
Background: Kallikrein 3 (KLK3), also known as Prostate Specific Antigen (PSA), is a member of the glandular kallikrein subfamily of serine proteases (1). It is produced by prostate epithelial cells and is secreted into prostatic ducts. Upon cleavage of 7 N-terminal amino acids (2), it is activated to liquefy semen in the seminal coagulum. Although PSA/KLK3 is produced in healthy individuals, investigators have found abnormally high levels in the blood of men with advanced prostate cancer (3,4).
Storage: Store at 4℃. Avoid freeze / thaw cycles.
Recommended Dilutions: WB 1:500 - 1:2000, IHC 1:50 - 1:200, FC 1:50 - 1:200

Target (Information from UniProt)
Function: Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.
Sequence Similarities: Belongs to the peptidase S1 family. Kallikrein subfamily.
Cellular Location: Secreted.

Western Blot - Anti-KLK3 Antibody from ABclonal (A1200) - Antibody Supply Service
Western blot analysis of Raji cell lysate using KLK3 antibody.

Product Code - A1200
Size Price Quantity
50µl £199
100µl £307
200µl £452

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