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Anti-Nestin Antibody

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ABclonal
A11344
Details
Description: Mouse monoclonal antibody to Nestin.
Category: Primary Antibodies
Applications: WB, IHC, IF, IP
Host: Mouse
Clonality: Monoclonal
Isotype: IgG
Reactivity: Human
UniProt: P48681
Gene ID: 10763
Immunogen: Recombinant protein of human NES
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonyms: Nbla00170
Purification: Affinity purification
Background: This gene encodes a member of the intermediate filament protein family and is expressed primarily in nerve cells.
Storage: Store at -20℃. Avoid freeze / thaw cycles.
Recommended Dilutions: WB 1:500 - 1:2000, IHC 1:50 - 1:100, IF 1:50 - 1:100, IP 1:20 - 1:50

Target (Information from UniProt)
Function: Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells (By similarity).
Tissue Specificity: CNS stem cells.
Sequence Similarities: Belongs to the intermediate filament family.
Post-Translational Modification: Constitutively phosphorylated. This increases during mitosis when the cytoplasmic intermediate filament network is reorganized (By similarity).

Product Code - A11344
Size Price Quantity
100µl £307
200µl £452

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