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Anti-TNNT2 Antibody

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ABclonal
A11209
Overview
Name: Anti-TNNT2 Antibody
Description: Mouse monoclonal antibody to TNNT2.
Applications: WB, IHC, IF, FC
Dilutions: WB 1:500 - 1:2000, IHC 1:50 - 1:100, IF 1:50 - 1:100, FC 1:20 - 1:50
Reactivity: Human
Immunogen: A synthetic peptide of human TNNT2
Host: Mouse
Clonality: Monoclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at -20℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
Tissue Specificity: Heart. The fetal heart shows a greater expression in the atrium than in the ventricle, while the adult heart shows a greater expression in the ventricle than in the atrium. Isoform 6 predominates in normal adult heart. Isoforms 1, 7 and 8 are expressed in fetal heart. Isoform 7 is also expressed in failing adult heart.
Involvement in Disease: Cardiomyopathy, familial hypertrophic 2: A hereditary heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope, collapse, palpitations, and chest pain. They can be readily provoked by exercise. The disorder has inter- and intrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiac death.

Cardiomyopathy, dilated 1D: A disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.

Cardiomyopathy, familial restrictive 3: A heart disorder characterized by impaired filling of the ventricles with reduced diastolic volume, in the presence of normal or near normal wall thickness and systolic function.
Sequence Similarities: Belongs to the troponin T family.
Post-Translational Modification: Phosphorylation at Thr-213 by PRKCA induces significant reduction in myofilament calcium sensitivity and actomyosin ATPase activity.
UniProt: P45379
Gene ID: 7139
Synonyms: Cardiac muscle troponin T Antibody
Cardiac Troponin T Antibody
Cardiomyopathy dilated 1D (autosomal dominant) Antibody
Cardiomyopathy hypertrophic 2 Antibody
CMD1D Antibody
CMH2 Antibody
CMPD2 Antibody
cTnT Antibody
LVNC6 Antibody
MGC3889 Antibody
OTTHUMP00000033864 Antibody
OTTHUMP00000033865 Antibody
OTTHUMP00000033866 Antibody
OTTHUMP00000033867 Antibody
OTTHUMP00000033870 Antibody
OTTHUMP00000218095 Antibody
RCM3 Antibody
TNNT 2 Antibody
TNNT1 Antibody
TNNT2_HUMAN Antibody
TNNT3 Antibody
TnTc Antibody
Troponin T cardiac muscle Antibody
Troponin T type 1 Antibody
Troponin T type 1 (skeletal, slow) Antibody
Troponin T type 2 Antibody
Troponin T type 2 (cardiac) Antibody
Troponin T type 2 cardiac Antibody
Troponin T type 3 Antibody
Troponin T type 3 (skeletal, fast) Antibody
Troponin T, cardiac muscle Antibody
Troponin T1 + T2 + T3 Antibody
Troponin T2 cardiac Antibody

Images
Western Blot - Anti-TNNT2 Antibody from ABclonal (A11209) - Antibody Supply Service
Western blot analysis of extracts of mouse heart cells, using TNNT2 antibody.

Product Code - A11209
Size Price Quantity
100µl £307
200µl £452

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