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Anti-IL6 Antibody

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ABclonal
A11093
Overview
Name: Anti-IL6 Antibody
Description: Mouse monoclonal antibody to IL6.
Applications: WB, IF, IP
Dilutions: WB 1:500 - 1:2000, IF 1:50 - 1:100, IP 1:20 - 1:50
Reactivity: Human
Immunogen: Recombinant protein of human IL6
Host: Mouse
Clonality: Monoclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at -20℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.
Involvement in Disease: Rheumatoid arthritis systemic juvenile: An inflammatory articular disorder with systemic-onset beginning before the age of 16. It represents a subgroup of juvenile arthritis associated with severe extraarticular features and occasionally fatal complications. During active phases of the disorder, patients display a typical daily spiking fever, an evanescent macular rash, lymphadenopathy, hepatosplenomegaly, serositis, myalgia and arthritis.
Sequence Similarities: Belongs to the IL-6 superfamily.
Post-Translational Modification: N- and O-glycosylated.
Cellular Location: Secreted.
UniProt: P05231
Gene ID: 3569
Synonyms: Interleukin BSF 2 Antibody
B cell differentiation factor Antibody
B cell stimulatory factor 2 Antibody
B-cell stimulatory factor 2 Antibody
BSF 2 Antibody
BSF-2 Antibody
BSF2 Antibody
CDF Antibody
CTL differentiation factor Antibody
Hepatocyte stimulatory factor Antibody
HGF Antibody
HSF Antibody
Hybridoma growth factor Antibody
Hybridoma growth factor Interferon beta-2 Antibody
IFN-beta-2 Antibody
IFNB2 Antibody
IL 6 Antibody
IL-6 Antibody
IL6_HUMAN Antibody
Interferon beta 2 Antibody
Interferon beta-2 Antibody
Interleukin 6 Antibody
Interleukin 6 (interferon beta 2) Antibody
Interleukin BSF 2 Antibody
Interleukin-6 Antibody

Product Code - A11093
Size Price Quantity
100µl £307
200µl £452

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