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Anti-CD11b Antibody

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Name: Anti-CD11b Antibody
Description: Mouse monoclonal antibody to CD11b.
Applications: IHC, IF, FC
Dilutions: IHC 1:50 - 1:100, IF 1:50 - 1:100, FC 1:20 - 1:50
Reactivity: Human
Immunogen: Recombinant protein of human ITGAM
Host: Mouse
Clonality: Monoclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at -20℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.
Tissue Specificity: Predominantly expressed in monocytes and granulocytes.
Involvement in Disease: Systemic lupus erythematosus 6: A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.
Sequence Similarities: Belongs to the integrin alpha chain family.
Cellular Location: Membrane.
UniProt: P11215
Gene ID: 3684
Synonyms: Antigen CD11b (p170) Antibody
Antigen CD11b p170 Antibody
CD11 antigen like family member B Antibody
CD11 antigen like family member C Antibody
CD11 antigen-like family member B Antibody
CD11b/c Antibody
CD11b/CD18 Antibody
CD11C Antibody
CD49d Antibody
Cell surface glycoprotein MAC 1 subunit alpha Antibody
Cell surface glycoprotein MAC-1 subunit alpha Antibody
Complement component 3 receptor 3 subunit Antibody
Complement Component Receptor 3 Alpha Antibody
Complement receptor type 3, alpha subunit Antibody
CR 3 alpha chain Antibody
CR 3 alpha chain (CR3A) Antibody
CR-3 alpha chain Antibody
CR3 Antibody
CR3A Antibody
F730045J24Rik Antibody
Integrin alpha M Antibody
Integrin alpha M chain Antibody
Integrin alpha X Antibody
Integrin alpha-M Antibody
Integrin beta 2 alpha subunit Antibody
Integrin subunit alpha M Antibody
Integrin, alpha M (complement component 3 receptor 3 subunit) Antibody
Integrin, alpha X (antigen CD11C (p150), alpha polypeptide) Antibody
Integrin, alpha X (complement component 3 receptor 4 subunit) Antibody
ITGAM Antibody
ITGAX Antibody
Leu M5, alpha subunit Antibody
Leukocyte adhesion glycoprotein p150,95 alpha chain Antibody
Leukocyte adhesion receptor MO1 Antibody
Leukocyte adhesion receptor p150,95 Antibody
Leukocyte surface antigen p150,95, alpha subunit Antibody
Ly-40 Antibody
MAC 1 Antibody
Mac-1a Antibody
MAC1 Antibody
Mac1, alpha subunit Antibody
MAC1A Antibody
Macrophage antigen alpha polypeptide Antibody
MGC117044 Antibody
Mo1, alpha subunit Antibody
MO1A Antibody
Myeloid membrane antigen, alpha subunit Antibody
Neutrophil adherence receptor Antibody
Neutrophil adherence receptor alpha M subunit Antibody
OTTHUMP00000163299 Antibody
p150 95 integrin alpha chain Antibody
SLEB6 Antibody

Product Code - A11057
Size Price Quantity
100µl £307
200µl £452

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