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Anti-CD8 Antibody

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ABclonal
A11033
Overview
Name: Anti-CD8 Antibody
Description: Rabbit monoclonal antibody to CD8.
Applications: WB, IHC, IF
Dilutions: WB 1:500 - 1:2000, IHC 1:50 - 1:200, ICC 1:50 - 1:200, IF 1:50 - 1:100
Reactivity: Human
Immunogen: Recombinant protein of human CD8A
Host: Rabbit
Clonality: Monoclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at -20℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains.
Involvement in Disease: CD8 deficiency, familial: An immunologic defect characterized by absence of CD8+ cells, leading to recurrent bacterial infections.
Post-Translational Modification: All of the five most C-terminal cysteines form inter-chain disulfide bonds in dimers and higher multimers, while the four N-terminal cysteines do not.
Cellular Location: Cell membrane.
UniProt: P01732
Gene ID: 925
Synonyms: alpha polypeptide (p32) Antibody
CD8 alpha Antibody
CD8 antigen alpha polypeptide Antibody
CD8 antigen alpha polypeptide (p32) Antibody
CD8 antigen, alpha polypeptide (p32) Antibody
CD8a Antibody
CD8A antigen Antibody
CD8A molecule Antibody
CD8A_HUMAN Antibody
Leu2 Antibody
Leu2 T lymphocyte antigen Antibody
Ly3 Antibody
LYT3 Antibody
MAL Antibody
OKT8 T cell antigen Antibody
OTTHUMP00000160760 Antibody
OTTHUMP00000160764 Antibody
OTTHUMP00000203528 Antibody
OTTHUMP00000203721 Antibody
p32 Antibody
T cell antigen Leu2 Antibody
T cell co receptor Antibody
T-cell surface glycoprotein CD8 alpha chain Antibody
T-lymphocyte differentiation antigen T8/Leu-2 Antibody
T8 T cell antigen Antibody
T8/Leu-2 T-lymphocyte differentiation antigen Antibody

Images
Western Blot - Anti-CD8 Antibody from ABclonal (A11033) - Antibody Supply Service
Western blot analysis of extracts of various cells, using CD8A antibody.
Immunohistochemistry - Anti-CD8 Antibody from ABclonal (A11033) - Antibody Supply Service
Immunohistochemistry of paraffin-embedded human spleen using CD8A antibody at dilution of 1:100 (40x lens).
Immunofluorescence - Anti-CD8 Antibody from ABclonal (A11033) - Antibody Supply Service
Immunofluorescence analysis of Hela cell using CD8A antibody.
Immunofluorescence - Anti-CD8 Antibody from ABclonal (A11033) - Antibody Supply Service
Immunofluorescence analysis of CRC cell using CD8A antibody.

Product Code - A11033
Size Price Quantity
100µl £372
200µl £565

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