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Anti-MMP-9 Antibody

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ABclonal
A11014
Overview
Name: Anti-MMP-9 Antibody
Description: Mouse monoclonal antibody to MMP-9.
Applications: WB, IHC, IF, IP
Dilutions: WB 1:500 - 1:2000, IHC 1:50 - 1:100, IF 1:50 - 1:100, IP 1:20 - 1:50
Reactivity: Human
Immunogen: A synthetic peptide of human MMP9
Host: Mouse
Clonality: Monoclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at -20℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide.
Tissue Specificity: Produced by normal alveolar macrophages and granulocytes.
Involvement in Disease: Intervertebral disc disease: A common musculo-skeletal disorder caused by degeneration of intervertebral disks of the lumbar spine. It results in low-back pain and unilateral leg pain.

Metaphyseal anadysplasia 2: A bone development disorder characterized by skeletal anomalies that resolve spontaneously with age. Clinical characteristics are evident from the first months of life and include slight shortness of stature and a mild varus deformity of the legs. Patients attain a normal stature in adolescence and show improvement or complete resolution of varus deformity of the legs and rhizomelic micromelia.
Sequence Similarities: Belongs to the peptidase M10A family.
Post-Translational Modification: Processing of the precursor yields different active forms of 64, 67 and 82 kDa. Sequentially processing by MMP3 yields the 82 kDa matrix metalloproteinase-9.
Cellular Location: Secreted > Extracellular space > Extracellular matrix.
UniProt: P14780
Gene ID: 4318
Synonyms: 82 kDa matrix metalloproteinase-9 Antibody
92 kDa gelatinase Antibody
92 kDa type IV collagenase Antibody
CLG 4B Antibody
CLG4B Antibody
Collagenase Type 4 beta Antibody
Collagenase type IV 92 KD Antibody
EC 3.4.24.35 Antibody
Gelatinase 92 KD Antibody
Gelatinase B Antibody
Gelatinase beta Antibody
GelatinaseB Antibody
GELB Antibody
Macrophage gelatinase Antibody
MANDP2 Antibody
Matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) Antibody
Matrix Metalloproteinase 9 Antibody
MMP 9 Antibody
MMP9 Antibody
MMP9_HUMAN Antibody
Type V collagenase Antibody

Images
Western Blot - Anti-MMP-9 Antibody from ABclonal (A11014) - Antibody Supply Service
Western blot analysis of extracts of PBL cells, using MMP9 antibody.

Product Code - A11014
Size Price Quantity
100µl £307
200µl £452

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