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Anti-MMS19 Antibody

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ABclonal
A10944
Overview
Name: Anti-MMS19 Antibody
Description: Rabbit polyclonal antibody to MMS19.
Applications: WB
Dilutions: WB 1:500 - 1:2000
Reactivity: Human
Immunogen: A synthetic Peptide of human MMS19
Protein Length: 1030
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at 4℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as ERCC2/XPD, FANCJ and RTEL1, thereby playing a key role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription. As part of the mitotic spindle-associated MMXD complex, plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD. Indirectly acts as a transcriptional coactivator of estrogen receptor (ER), via its role in iron-sulfur insertion into some component of the TFIIH-machinery.
Tissue Specificity: Ubiquitously expressed with higher expression in testis.
Sequence Similarities: Belongs to the MET18/MMS19 family.
Cellular Location: Nucleus. Cytoplasm > Cytoskeleton > Spindle.
UniProt: Q96T76
Gene ID: 64210
Synonyms: hMMS19 Antibody
homolog of yeast MMS19 Antibody
MET18 Antibody
MET18 homolog Antibody
MET18MMS19 nucleotide excision repair homolog (S. cerevisiae) Antibody
MMS19 nucleotide excision repair protein homolog Antibody
MMS19 nucleotide excision repair, S. cerevisiae, homolog of Antibody
MMS19-like (MET18 homolog, S. cerevisiae) Antibody
MMS19-like protein Antibody
MMS19L Antibody
MMS19_HUMAN Antibody

Images
Western Blot - Anti-MMS19 Antibody from ABclonal (A10944) - Antibody Supply Service
Western blot analysis of extracts of various cell lines, using MMS19 antibody.

Product Code - A10944
Size Price Quantity
100µl £243
200µl £372

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