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Anti-Cytokeratin-7 Antibody

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ABclonal
A10934
Details
Description: Mouse monoclonal antibody to Cytokeratin-7.
Category: Primary Antibodies
Applications: WB, IHC
Host: Mouse
Clonality: Monoclonal
Isotype: IgG
Reactivity: Human
UniProt: P08729
Gene ID: 3855
Immunogen: A synthetic peptide of human KRT7
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonyms: K7; CK7; SCL; K2C7
Purification: Affinity purification
Background: The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described.
Storage: Store at -20℃. Avoid freeze / thaw cycles.
Recommended Dilutions: WB 1:500 - 1:2000, IHC 1:50 - 1:100

Target (Information from UniProt)
Function: Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).
Tissue Specificity: Expressed in cultured epidermal, bronchial and mesothelial cells but absent in colon, ectocervix and liver. Observed throughout the glandular cells in the junction between stomach and esophagus but is absent in the esophagus.
Sequence Similarities: Belongs to the intermediate filament family.
Post-Translational Modification: Arg-20 is dimethylated, probably to asymmetric dimethylarginine.
Cellular Location: Cytoplasm.

Images
Western Blot - Anti-Cytokeratin-7 Antibody from ABclonal (A10934) - Antibody Supply Service
Western blot analysis of extracts of HepG2 cells, using KRT7 antibody.

Product Code - A10934
Size Price Quantity
100µl £307
200µl £452

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