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Anti-ICAM1 Antibody

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ABclonal
A10909
Details
Description: Mouse monoclonal antibody to ICAM1.
Category: Primary Antibodies
Applications: WB, IHC, IF
Host: Mouse
Clonality: Monoclonal
Isotype: IgG
Reactivity: Human
UniProt: P05362
Gene ID: 3383
Immunogen: A synthetic peptide of human ICAM1
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonyms: BB2; CD54; P3.58
Purification: Affinity purification
Background: This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor.
Storage: Store at -20℃. Avoid freeze / thaw cycles.
Recommended Dilutions: WB 1:500 - 1:2000, IHC 1:50 - 1:100, IF 1:50 - 1:100

Target (Information from UniProt)
Function: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation.
Sequence Similarities: Belongs to the immunoglobulin superfamily. ICAM family.
Post-Translational Modification: Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis.
Cellular Location: Membrane.

Images
Western Blot - Anti-ICAM1 Antibody from ABclonal (A10909) - Antibody Supply Service
Western blot analysis of extracts of HUVEC cells, using ICAM1 antibody.

Product Code - A10909
Size Price Quantity
100µl £307
200µl £452

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