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Anti-SMC2 Antibody

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ABclonal
A10908
Overview
Name: Anti-SMC2 Antibody
Description: Rabbit polyclonal antibody to SMC2.
Applications: WB
Dilutions: WB 1:500 - 1:2000
Reactivity: Human
Immunogen: A synthetic Peptide of human SMC2
Protein Length: 1197
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at 4℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
Sequence Similarities: Belongs to the SMC family. SMC2 subfamily.
Cellular Location: Nucleus. Cytoplasm. Chromosome.

In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, the regulatory subunits of the complex are phosphorylated by CDC2, leading to condensin's association with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase.
UniProt: O95347
Gene ID: 10592
Synonyms: CAP E Antibody
CAPE Antibody
Chromosome associated protein E Antibody
Chromosome-associated protein E Antibody
DKFZP434G099 Antibody
FLJ10093 Antibody
hCAP E Antibody
hCAP-E Antibody
hCAPE Antibody
MGC138182 Antibody
PRO0324 Antibody
RAB 33B Antibody
RAB33B Antibody
RAB33B member RAS oncogene family Antibody
Ras related protein Rab 33B Antibody
Ras related protein Rab33B Antibody
Ras-associated protein RAB33B Antibody
Ras-related protein Rab-33B Antibody
RB33B_HUMAN Antibody
SMC 2 Antibody
SMC protein 2 Antibody
SMC-2 Antibody
SMC2 L1 Antibody
SMC2L1 Antibody
SMC2_HUMAN Antibody
Structural maintenance of chromosomes (SMC) family member chromosome associated protein E Antibody
Structural maintenance of chromosomes 2 Antibody
Structural maintenance of chromosomes 2 like 1 Antibody
Structural maintenance of chromosomes 2 yeast like 1 Antibody
Structural maintenance of chromosomes protein 2 Antibody
XCAP E homolog Antibody
XCAP-E homolog Antibody
XCAPE homolog Antibody

Images
Western Blot - Anti-SMC2 Antibody from ABclonal (A10908) - Antibody Supply Service
Western blot analysis of extracts of various cell lines, using SMC2 antibody.

Product Code - A10908
Size Price Quantity
100µl £243
200µl £372

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