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Anti-FOLH1 Antibody

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ABclonal
A10863
Overview
Name: Anti-FOLH1 Antibody
Description: Rabbit polyclonal antibody to FOLH1.
Applications: WB, IHC, IF
Dilutions: WB 1:500 - 1:1000, IHC 1:20 - 1:50, IF 1:20 - 1:50
Reactivity: Human
Immunogen: A synthetic Peptide of human FOLH1
Protein Length: 750
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at 4℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Involved in prostate tumor progression.
Tissue Specificity: Highly expressed in prostate epithelium. Detected in urinary bladder, kidney, testis, ovary, fallopian tube, breast, adrenal gland, liver, esophagus, stomach, small intestine, colon and brain (at protein level). Detected in the small intestine, brain, kidney, liver, spleen, colon, trachea, spinal cord and the capillary endothelium of a variety of tumors. Expressed specifically in jejunum brush border membranes. In the brain, highly expressed in the ventral striatum and brain stem. Also expressed in fetal liver and kidney. Isoform PSMA' is the most abundant form in normal prostate. Isoform PSMA-1 is the most abundant form in primary prostate tumors. Isoform PSMA-3 is also found in normal prostate as well as in brain and liver. Isoform PSMA-9 is specifically expressed in prostate cancer.
Sequence Similarities: Belongs to the peptidase M28 family. M28B subfamily.
Post-Translational Modification: The first two amino acids at the N-terminus of isoform PSMA' appear to be cleaved by limited proteolysis.
Cellular Location: Cell membrane.
UniProt: Q04609
Gene ID: 2346
Synonyms: Cell growth inhibiting protein 27 Antibody
Cell growth-inhibiting gene 27 protein Antibody
FGCP Antibody
Folate hydrolase Antibody
Folate hydrolase (prostate-specific membrane antigen) 1 Antibody
Folate hydrolase 1 Antibody
Folate hydrolase prostate specific membrane antigen 1 Antibody
FOLH Antibody
FOLH 1 Antibody
FOLH1_HUMAN Antibody
Folylpoly gamma glutamate carboxypeptidase Antibody
Folylpoly-gamma-glutamate carboxypeptidase Antibody
GCP 2 Antibody
GCP II Antibody
GCP2 Antibody
GCPII Antibody
GIG27 Antibody
Glutamate carboxylase II Antibody
Glutamate carboxypeptidase 2 Antibody
Glutamate carboxypeptidase II Antibody
Membrane glutamate carboxypeptidase Antibody
mGCP Antibody
N acetylated alpha linked acidic dipeptidase 1 Antibody
N-acetylated-alpha-linked acidic dipeptidase I Antibody
NAALAD 1 Antibody
NAALAD1 Antibody
NAALAdase Antibody
NAALADase I Antibody
Prostate specific membrane antigen Antibody
Prostate specific membrane antigen variant F Antibody
Prostate-specific membrane antigen Antibody
PSM Antibody
PSMA Antibody
Pteroylpoly gamma glutamate carboxypeptidase Antibody
Pteroylpoly-gamma-glutamate carboxypeptidase Antibody

Images
Western Blot - Anti-FOLH1 Antibody from ABclonal (A10863) - Antibody Supply Service
Western blot analysis of extracts of various cell lines, using FOLH1 antibody.

Product Code - A10863
Size Price Quantity
100µl £243
200µl £372

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