phone icon
+44 (0)1223 298875

Anti-Estrogen Related Recepr alpha (ERR alpha) Antibody

file icon Datasheet
ABclonal
A10858
Overview
Name: Anti-Estrogen Related Recepr alpha (ERR alpha) Antibody
Description: Mouse monoclonal antibody to Estrogen Related Recepr alpha (ERR alpha).
Applications: WB, IP
Dilutions: WB 1:500 - 1:2000, IP 1:20 - 1:50
Reactivity: Human
Immunogen: A synthetic peptide of human ESRRA
Host: Mouse
Clonality: Monoclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at -20℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism. Induces the expression of PERM1 in the skeletal muscle.
Sequence Similarities: Belongs to the nuclear hormone receptor family. NR3 subfamily.
Post-Translational Modification: Phosphorylation on Ser-19 enhances sumoylation on Lys-14 increasing repression of transcriptional activity.
Cellular Location: Nucleus.
UniProt: P11474
Gene ID: 2101

Product Code - A10858
Size Price Quantity
100µl £307
200µl £452

or
Request a quotation
Contact us directly to order
  • call icon +44 (0)1223 298875
  • +44 (0)1223 281447
  • email icon orders@ab-y-ss.com
Product Quality
  • guarantee icon
  • We promise guaranteed product quality
  • and expert customer service.
Shipping Information
  • £20 to United Kingdom
  • £35 to Europe