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Anti-UPK2 Antibody

file icon Datasheet
Description: Rabbit polyclonal antibody to UPK2.
Category: Primary Antibodies
Applications: WB
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Reactivity: Human
UniProt: O00526
Gene ID: 7379
Immunogen: Recombinant protein of human UPK2
Protein Length: 184
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonyms: UP2; UPII
Purification: Affinity purification
Background: This gene encodes one of the proteins of the highly conserved urothelium-specific integral membrane proteins of the asymmetric unit membrane which forms urothelium apical plaques in mammals. The asymmetric unit membrane is believed to strengthen the urothelium by preventing cell rupture during bladder distention. The encoded protein is expressed in the peripheral blood of bladder cancer patients with transitional cell carcinomas.
Storage: Store at -20℃. Avoid freeze / thaw cycles.
Recommended Dilutions: WB 1:500 - 1:2000

Target (Information from UniProt)
Function: Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in regulating the assembly of the AUM (By similarity).
Tissue Specificity: Expressed in ureter.
Sequence Similarities: Belongs to the uroplakin-2 family.
Cellular Location: Cell membrane.

Heterodimer formation with UPK1A is a prerequisite to exit out of the endoplasmic reticulum (ER).

Western Blot - Anti-UPK2 Antibody from ABclonal (A10813) - Antibody Supply Service
Western blot analysis of extracts of B cells, using UPK2 antibody.

Product Code - A10813
Size Price Quantity
50µl £148
100µl £243
200µl £372

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