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Anti-CD151 Antibody

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ABclonal
A10804
Details
Description: Mouse monoclonal antibody to CD151.
Category: Primary Antibodies
Applications: WB, IHC, IF, IP
Host: Mouse
Clonality: Monoclonal
Isotype: IgG
Reactivity: Human
UniProt: P48509
Gene ID: 977
Immunogen: A synthetic peptide of human CD151
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonyms: GP27; MER2; RAPH; SFA1; PETA-3; TSPAN24
Purification: Affinity purification
Background: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene.
Storage: Store at -20℃. Avoid freeze / thaw cycles.
Recommended Dilutions: WB 1:500 - 1:2000, IHC 1:50 - 1:100, IF 1:50 - 1:100, IP 1:20 - 1:50

Target (Information from UniProt)
Function: Essential for the proper assembly of the glomerular and tubular basement membranes in kidney.
Tissue Specificity: Expressed in a variety of tissues including vascular endothelium and epidermis. Expressed on erythroid cells, with a higher level of expression in erythroid precursors than on mature erythrocytes.
Involvement in Disease: Nephropathy with pretibial epidermolysis bullosa and deafness: A disorder characterized by the association of hereditary nephritis, epidermolysis bullosa, deafness, and beta-thalassemia minor.
Sequence Similarities: Belongs to the tetraspanin (TM4SF) family.
Cellular Location: Membrane.

Images
Western Blot - Anti-CD151 Antibody from ABclonal (A10804) - Antibody Supply Service
Western blot analysis of extracts of Human platelet cells, using CD151 antibody.

Product Code - A10804
Size Price Quantity
100µl £307
200µl £452

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