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Anti-CD44 Antibody

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ABclonal
A10801
Overview
Name: Anti-CD44 Antibody
Description: Mouse monoclonal antibody to CD44.
Applications: WB, IHC, FC
Dilutions: WB 1:500 - 1:2000, IHC 1:50 - 1:100, FC 1:20 - 1:50
Reactivity: Human
Immunogen: A synthetic peptide of human CD44
Host: Mouse
Clonality: Monoclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at -20℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events. Receptor for LGALS9; the interaction enhances binding of SMAD3 to the FOXP3 promoter, leading to up-regulation of FOXP3 expression and increased induced regulatory T (iTreg) cell stability and suppressive function (By similarity).
Tissue Specificity: Isoform 10 (epithelial isoform) is expressed by cells of epithelium and highly expressed by carcinomas. Expression is repressed in neuroblastoma cells.
Post-Translational Modification: Proteolytically cleaved in the extracellular matrix by specific proteinases (possibly MMPs) in several cell lines and tumors.
Cellular Location: Cell membrane.

Colocalizes with actin in membrane protrusions at wounding edges.
UniProt: P16070
Gene ID: 960
Synonyms: LHR Antibody
BA-1 Antibody
CD 44 Antibody
CD44 (phospho S706) Antibody
CD44 antigen Antibody
CD44 molecule Antibody
CD44 molecule (Indian blood group) Antibody
CD44(v3-v10) Antibody
CD44v6 Antibody
CD44_HUMAN Antibody
CDw44 Antibody
Cell surface glycoprotein CD44 Antibody
chondroitin sulfate proteoglycan 8 Antibody
CSPG8 Antibody
ECMR-III Antibody
Epican Antibody
Extracellular matrix receptor III Antibody
GP90 lymphocyte homing/adhesion receptor Antibody
HCAM Antibody
HCELL Antibody
hematopoietic cell E- and L-selectin ligand Antibody
Heparan sulfate proteoglycan Antibody
Hermes antigen Antibody
homing function and Indian blood group system Antibody
HSA Antibody
HUTCH I Antibody
HUTCH-I Antibody
HUTCH1 Antibody
Hyaluronate receptor Antibody
Ihr Antibody
IN Antibody
MC56 Antibody
MDU2 Antibody
MDU3 Antibody
MGC10468 Antibody
MIC4 Antibody
MUTCH I Antibody
MUTCH1 Antibody
PGP 1 Antibody
PGP-1 Antibody
PGP-I Antibody
PGP1 Antibody
Phagocytic glycoprotein 1 Antibody
Phagocytic glycoprotein I Antibody

Images
Western Blot - Anti-CD44 Antibody from ABclonal (A10801) - Antibody Supply Service
Western blot analysis of extracts of HeLa cells, using CD44 antibody.

Product Code - A10801
Size Price Quantity
100µl £307
200µl £452

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