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Anti-CD4 Antibody

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ABclonal
A10787
Overview
Name: Anti-CD4 Antibody
Description: Rabbit monoclonal antibody to CD4.
Applications: WB, IHC, IF
Dilutions: WB 1:500 - 1:2000, IHC 1:50 - 1:200, ICC 1:50 - 1:200, IF 1:50 - 1:100
Reactivity: Human
Immunogen: Recombinant protein of human CD4
Host: Rabbit
Clonality: Monoclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at -20℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.
Post-Translational Modification: Palmitoylation and association with LCK contribute to the enrichment of CD4 in lipid rafts.
Cellular Location: Cell membrane.

Localizes to lipid rafts. Removed from plasma membrane by HIV-1 Nef protein that increases clathrin-dependent endocytosis of this antigen to target it to lysosomal degradation. Cell surface expression is also down-modulated by HIV-1 Envelope polyprotein gp160 that interacts with, and sequesters CD4 in the endoplasmic reticulum.
UniProt: P01730
Gene ID: 920
Synonyms: CD 4 Antibody
CD4 (L3T4) Antibody
CD4 (phospho S433) Antibody
CD4 antigen Antibody
CD4 antigen (p55) Antibody
CD4 molecule Antibody
CD4 receptor Antibody
CD4+ Lymphocyte deficiency, included Antibody
CD4mut Antibody
CD4_HUMAN Antibody
L3T4 Antibody
Leu3 Antibody
Ly-4 Antibody
Lymphocyte antigen CD4 Antibody
MGC165891 Antibody
OTTHUMP00000238897 Antibody
p55 Antibody
T cell antigen T4 Antibody
T cell antigen T4/LEU3 Antibody
T cell differentiation antigen L3T4 Antibody
T cell OKT4 deficiency, included Antibody
T cell surface antigen T4/Leu 3 Antibody
T cell surface antigen T4/Leu3 Antibody
T cell surface glycoprotein CD4 Antibody
T-cell surface antigen T4/Leu-3 Antibody
T-cell surface glycoprotein CD4 Antibody
W3/25 Antibody
W3/25 antigen Antibody

Images
Western Blot - Anti-CD4 Antibody from ABclonal (A10787) - Antibody Supply Service
Western blot analysis of extracts of Jurkat cells, using CD4 antibody.
Immunohistochemistry - Anti-CD4 Antibody from ABclonal (A10787) - Antibody Supply Service
Immunohistochemistry of paraffin-embedded human spleen using CD4 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - Anti-CD4 Antibody from ABclonal (A10787) - Antibody Supply Service
Immunohistochemistry of paraffin-embedded human tonsil using CD4 antibody at dilution of 1:100 (40x lens).
Immunofluorescence - Anti-CD4 Antibody from ABclonal (A10787) - Antibody Supply Service
Immunofluorescence analysis of CRC cell using CD4 antibody.
Immunofluorescence - Anti-CD4 Antibody from ABclonal (A10787) - Antibody Supply Service
Immunofluorescence analysis of A549 cell using CD4 antibody.

Product Code - A10787
Size Price Quantity
100µl £372
200µl £565

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