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Anti-SCN2A Antibody

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ABclonal
A10574
Overview
Name: Anti-SCN2A Antibody
Description: Rabbit polyclonal antibody to SCN2A.
Applications: WB
Dilutions: WB 1:1000 - 1:2000
Reactivity: Human
Immunogen: Recombinant protein of human SCN2A
Protein Length: 2005
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at -20℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
Involvement in Disease: Seizures, benign familial infantile, 3: A form of benign familial infantile epilepsy, a neurologic disorder characterized by afebrile seizures occurring in clusters during the first year of life, without neurologic sequelae. BFIS3 inheritance is autosomal dominant.

Epileptic encephalopathy, early infantile, 11: An autosomal dominant seizure disorder characterized by neonatal or infantile onset of refractory seizures with resultant delayed neurologic development and persistent neurologic abnormalities. Patients may progress to West syndrome, which is characterized by tonic spasms with clustering, arrest of psychomotor development, and hypsarrhythmia on EEG.
Sequence Similarities: Belongs to the sodium channel (TC 1.A.1.10) family. Nav1.2/SCN2A subfamily.
Post-Translational Modification: May be ubiquitinated by NEDD4L; which would promote its endocytosis.
Cellular Location: Cell membrane.
UniProt: Q99250
Gene ID: 6326
Synonyms: HBSC II Antibody
HH1 Antibody
hNaN Antibody
hNE-Na Antibody
hPN3 Antibody
KIAA1356 Antibody
MED Antibody
NAC1 Antibody
NAC2 Antibody
NAC3 Antibody
NENA Antibody
Neuroendocrine sodium channel Antibody
pan Sodium Channel Antibody
Peripheral nerve sodium channel 3 Antibody
Peripheral nerve sodium channel 5 Antibody
Peripheral sodium channel 1 Antibody
PN1 Antibody
PN3 Antibody
PN5 Antibody
SCN1 Antibody
SCN10A Antibody
SCN11A Antibody
SCN12A Antibody
SCN1A Antibody
SCN2A1 Antibody
SCN2A2 Antibody
SCN2A_HUMAN Antibody
SCN3A Antibody
SCN4A Antibody
SCN5A Antibody
SCN8A Antibody
SCN9A Antibody
Sensory neuron sodium channel 2 Antibody
SkM1 Antibody
SNS2 Antibody
Sodium channel protein brain I subunit alpha Antibody
Sodium channel protein brain II subunit alpha Antibody
Sodium channel protein brain III subunit alpha Antibody
Sodium channel protein cardiac muscle subunit alpha Antibody
Sodium channel protein skeletal muscle subunit alpha Antibody
Sodium channel protein type 1 subunit alpha Antibody
Sodium channel protein type 10 subunit alpha Antibody
Sodium channel protein type 11 subunit alpha Antibody
Sodium channel protein type 2 subunit alpha Antibody
Sodium channel protein type 3 subunit alpha Antibody
Sodium channel protein type 4 subunit alpha Antibody
Sodium channel protein type 5 subunit alpha Antibody
Sodium channel protein type 8 subunit alpha Antibody
Sodium channel protein type 9 subunit alpha Antibody
Sodium channel protein type II subunit alpha Antibody
Sodium channel protein type III subunit alpha Antibody
Sodium channel protein type IV subunit alpha Antibody
Sodium channel protein type IX subunit alpha Antibody
Sodium channel protein type V subunit alpha Antibody
Sodium channel protein type VIII subunit alpha Antibody
Sodium channel protein type X subunit alpha Antibody
Sodium channel protein type XI subunit alpha Antibody
Sodium channel protein, brain II subunit alpha Antibody
Voltage gated sodium channel subunit alpha Nav1.2 Antibody
Voltage-gated sodium channel subtype III Antibody
Voltage-gated sodium channel subunit alpha Nav1.1 Antibody
Voltage-gated sodium channel subunit alpha Nav1.2 Antibody
Voltage-gated sodium channel subunit alpha Nav1.3 Antibody
Voltage-gated sodium channel subunit alpha Nav1.4 Antibody
Voltage-gated sodium channel subunit alpha Nav1.5 Antibody
Voltage-gated sodium channel subunit alpha Nav1.6 Antibody
Voltage-gated sodium channel subunit alpha Nav1.7 Antibody
Voltage-gated sodium channel subunit alpha Nav1.8 Antibody
Voltage-gated sodium channel subunit alpha Nav1.9 Antibody

Images
Western Blot - Anti-SCN2A Antibody from ABclonal (A10574) - Antibody Supply Service
Western blot analysis of extracts of various cells, using SCN2A antibody.

Product Code - A10574
Size Price Quantity
50µl £148
100µl £243
200µl £372

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