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Anti-LAMB2 Antibody

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ABclonal
A10565
Overview
Name: Anti-LAMB2 Antibody
Description: Rabbit polyclonal antibody to LAMB2.
Applications: WB
Dilutions: WB 1:1000 - 1:2000
Reactivity: Human
Immunogen: Recombinant protein of human LAMB2
Protein Length: 1798
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at -20℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
Involvement in Disease: Pierson syndrome: Characterized by nephrotic syndrome with neonatal onset, diffuse mesangial sclerosis and eye abnormalities with microcoria as the leading clinical feature. Death usually occurs within the first weeks of life. Disease severity depends on the mutation type: nontruncating LAMB2 mutations may display variable phenotypes ranging from a milder variant of Pierson syndrome to isolated congenital nephrotic syndrome.

Nephrotic syndrome 5 with or without ocular abnormalities: A form of nephrotic syndrome, a renal disease clinically characterized by severe proteinuria, resulting in complications such as hypoalbuminemia, hyperlipidemia and edema. Kidney biopsies show non-specific histologic changes such as focal segmental glomerulosclerosis and diffuse mesangial proliferation. Some affected individuals have an inherited steroid-resistant form and progress to end-stage renal failure. NPHS5 is characterized by very early onset of progressive renal failure. A subset of patients may develop mild ocular anomalies, such as myopia, nystagmus, and strabismus.
Cellular Location: Secreted > Extracellular space > Extracellular matrix > Basement membrane.

S-laminin is concentrated in the synaptic cleft of the neuromuscular junction.
UniProt: P55268
Gene ID: 3913
Synonyms: LAMB 2 Antibody
LAMB2_HUMAN Antibody
lamc1 Antibody
LAMC1_HUMAN Antibody
Lamin B2 Antibody
Lamin-B2 Antibody
Laminin B1s chain Antibody
Laminin B2 chain Antibody
Laminin beta 2 Antibody
Laminin gamma 1 Antibody
laminin S Antibody
Laminin subunit beta 2 Antibody
Laminin subunit beta-2 Antibody
Laminin subunit gamma-1 Antibody
laminin, beta 2 (laminin S) Antibody
Laminin, gamma 1 (formerly LAMB2) Antibody
Laminin-1 subunit gamma Antibody
Laminin-10 subunit gamma Antibody
Laminin-11 subunit beta Antibody
Laminin-11 subunit gamma Antibody
Laminin-14 subunit beta Antibody
Laminin-15 subunit beta Antibody
Laminin-2 subunit gamma Antibody
Laminin-3 subunit beta Antibody
Laminin-3 subunit gamma Antibody
Laminin-4 subunit beta Antibody
Laminin-4 subunit gamma Antibody
Laminin-6 subunit gamma Antibody
Laminin-7 subunit beta Antibody
Laminin-7 subunit gamma Antibody
Laminin-8 subunit gamma Antibody
Laminin-9 subunit beta Antibody
Laminin-9 subunit gamma Antibody
LAMS Antibody
LMN 2 Antibody
LMN B2 Antibody
LMN2 Antibody
LMNB 2 Antibody
LMNB2 Antibody
LMNB2_HUMAN Antibody
MGC2721 Antibody
MGC87297 Antibody
NPHS5 Antibody
RGD1563803 Antibody
S laminin Antibody
S-LAM beta Antibody
S-LAM gamma Antibody
S-laminin subunit beta Antibody
S-laminin subunit gamma Antibody
STX 6 Antibody
STX6 Antibody
STX6_HUMAN Antibody
Syntaxin 6 Antibody
Syntaxin-6 Antibody
Syntaxin6 Antibody

Images
Western Blot - Anti-LAMB2 Antibody from ABclonal (A10565) - Antibody Supply Service
Western blot analysis of extracts of LO2 cells, using LAMB2 antibody.

Product Code - A10565
Size Price Quantity
50µl £148
100µl £243
200µl £372

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