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Anti-TREM2 Antibody

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ABclonal
A10482
Overview
Name: Anti-TREM2 Antibody
Description: Rabbit polyclonal antibody to TREM2.
Applications: WB
Dilutions: WB 1:500 - 1:1000
Reactivity: Human
Immunogen: Recombinant protein of human TREM2
Protein Length: 230
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at -20℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: May have a role in chronic inflammations and may stimulate production of constitutive rather than inflammatory chemokines and cytokines. Forms a receptor signaling complex with TYROBP and triggers activation of the immune responses in macrophages and dendritic cells.
Tissue Specificity: Expressed on macrophages and dendritic cells but not on granulocytes or monocytes. In the CNS strongest expression seen in the basal ganglia, corpus callosum, medulla oblongata and spinal cord.
Involvement in Disease: Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy: Recessively inherited disease characterized by a combination of psychotic symptoms rapidly progressing to presenile dementia and bone cysts restricted to wrists and ankles. PLOSL has a global distribution, although most of the patients have been diagnosed in Finland and Japan, with an estimated population prevalence of 2x10(-6) in the Finns.
Cellular Location: Cell membrane.
UniProt: Q9NZC2
Gene ID: 54209
Synonyms: TREM 2 Antibody
TREM-2 Antibody
TREM2a Antibody
TREM2b Antibody
TREM2c Antibody
TREM2_HUMAN Antibody
Trggering receptor expressed on myeloid cells 2 Antibody
Trggering receptor expressed on myeloid cells 2a Antibody
Triggering receptor expressed on monocytes 2 Antibody
Triggering receptor expressed on myeloid cells 2 Antibody

Images
Western Blot - Anti-TREM2 Antibody from ABclonal (A10482) - Antibody Supply Service
Western blot analysis of extracts of mouse lung cells, using TREM2 antibody.

Product Code - A10482
Size Price Quantity
50µl £148
100µl £243
200µl £372

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