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Anti-JTB Antibody

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ABclonal
A10427
Overview
Name: Anti-JTB Antibody
Description: Rabbit polyclonal antibody to JTB.
Applications: WB
Dilutions: WB 1:500 - 1:2000
Reactivity: Human
Immunogen: Recombinant protein of human JTB
Protein Length: 146
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at -20℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: Required for normal cytokinesis during mitosis. Plays a role in the regulation of cell proliferation. May be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Increases AURKB activity. Inhibits apoptosis induced by TGFB1 (By similarity). Overexpression induces swelling of mitochondria and reduces mitochondrial membrane potential (By similarity).
Tissue Specificity: Ubiquitous. Expressed in all normal human tissues studied but overexpressed or underexpressed in many of their malignant counterparts.
Sequence Similarities: Belongs to the JTB family.
Cellular Location: Membrane. Mitochondrion. Cytoplasm. Cytoplasm > Cytoskeleton > Microtubule organizing center > Centrosome. Cytoplasm > Cytoskeleton > Spindle.

Detected at the centrosome and along spindle fibers during prophase and metaphase. Detected at the midbody during telophase.
UniProt: O76095
Gene ID: 10899
Synonyms: hJT Antibody
HJTB Antibody
HSPC222 Antibody
JTB_HUMAN Antibody
Jumping translocation breakpoint Antibody
Jumping translocation breakpoint protein Antibody
OTTHUMP00000034759 Antibody
PAR Antibody
PAR protein Antibody
Prostate androgen regulated protein Antibody
Prostate androgen-regulated protein Antibody
Protein JTB Antibody

Images
Western Blot - Anti-JTB Antibody from ABclonal (A10427) - Antibody Supply Service
Western blot analysis of extracts of various cell lines, using JTB antibody.

Product Code - A10427
Size Price Quantity
50µl £148
100µl £243
200µl £372

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