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Anti-ANKRD13A Antibody

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Description: Rabbit polyclonal antibody to ANKRD13A.
Category: Primary Antibodies
Applications: WB
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Reactivity: Human
UniProt: Q8IZ07
Gene ID: 88455
Immunogen: Recombinant protein of human ANKRD13A
Protein Length: 590
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonyms: ANKRD13; NY-REN-25
Purification: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles.
Recommended Dilutions: WB 1:500 - 1:2000

Target (Information from UniProt)
Function: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.
Post-Translational Modification: Monoubiquitinated, inhibits interaction with ubiquitinated EGFR.
Cellular Location: Cell membrane. Late endosome.

Interaction with EGFR may enhance association with the cell membrane.

Product Code - A10416
Size Price Quantity
50µl £148
100µl £243
200µl £372

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