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Anti-GNAT2 Antibody

file icon Datasheet
Description: Rabbit polyclonal antibody to GNAT2.
Category: Primary Antibodies
Applications: WB
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Reactivity: Human
UniProt: P19087
Gene ID: 2780
Immunogen: Recombinant protein of human GNAT2
Protein Length: 354
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonyms: ACHM4; GNATC
Purification: Affinity purification
Background: Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phoshodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in cones.
Storage: Store at -20℃. Avoid freeze / thaw cycles.
Recommended Dilutions: WB 1:500 - 1:2000

Target (Information from UniProt)
Function: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that performs the coupling between rhodopsin and cGMP-phosphodiesterase.
Tissue Specificity: Retinal rod outer segment.
Involvement in Disease: Achromatopsia 4: An ocular stationary disorder due to the absence of functioning cone photoreceptors in the retina. It is characterized by total colorblindness, low visual acuity, photophobia and nystagmus.
Sequence Similarities: Belongs to the G-alpha family. G(i/o/t/z) subfamily.

Western Blot - Anti-GNAT2 Antibody from ABclonal (A10352) - Antibody Supply Service
Western blot analysis of extracts of HepG2 cells, using GNAT2 antibody.

Product Code - A10352
Size Price Quantity
50µl £148
100µl £243
200µl £372

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