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Anti-CD276 Antibody

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Name: Anti-CD276 Antibody
Description: Rabbit polyclonal antibody to CD276.
Applications: WB
Dilutions: WB 1:500 - 1:2000
Reactivity: Human
Immunogen: Recombinant protein of human CD276
Protein Length: 534
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at -20℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling.
Tissue Specificity: Ubiquitous but not detectable in peripheral blood lymphocytes or granulocytes. Weakly expressed in resting monocytes. Expressed in dendritic cells derived from monocytes. Expressed in epithelial cells of sinonasal tissue. Expressed in extravillous trophoblast cells and Hofbauer cells of the first trimester placenta and term placenta.
Sequence Similarities: Belongs to the immunoglobulin superfamily. BTN/MOG family.
Cellular Location: Membrane.
UniProt: Q5ZPR3
Gene ID: 80381
Synonyms: 4Ig B7 H3 Antibody
4Ig-B7-H3 Antibody
AU016588 Antibody
B7 H3 Antibody
B7 homolog 3 Antibody
B7-H3 Antibody
B7H3 Antibody
B7RP-2 Antibody
CD276 antigen Antibody
CD276 molecule Antibody
CD276_HUMAN Antibody
CD_antigen=CD276 Antibody
Costimulatory molecule Antibody
Flags: Precursor Antibody
PSEC0249 Antibody
UNQ309/PRO352 Antibody

Western Blot - Anti-CD276 Antibody from ABclonal (A10347) - Antibody Supply Service
Western blot analysis of extracts of various cell lines, using CD276 antibody.

Product Code - A10347
Size Price Quantity
50µl £148
100µl £243
200µl £372

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