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Anti-BTN3A1 Antibody

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ABclonal
A10288
Details
Description: Rabbit polyclonal antibody to BTN3A1.
Category: Primary Antibodies
Applications: WB
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Reactivity: Human
UniProt: O00481
Gene ID: 11119
Immunogen: Recombinant protein of human BTN3A1
Protein Length: 513
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonyms: BTF5; BT3.1; CD277; BTN3.1
Purification: Affinity purification
Background: The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A1; MIM 613590) and BTN3 (e.g., BNT3A1) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010
Storage: Store at -20℃. Avoid freeze / thaw cycles.
Recommended Dilutions: WB 1:500 - 1:2000

Target (Information from UniProt)
Function: Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of activated T-cells. Regulates the release of cytokines and IFNG by activated T-cells. Mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate.
Tissue Specificity: Detected on T-cells, natural killer cells, dendritic cells and macrophages (at protein level). Ubiquitous. Highly expressed in heart, pancreas and lung, Moderately expressed in placenta, liver and muscle.
Sequence Similarities: Belongs to the immunoglobulin superfamily. BTN/MOG family.
Post-Translational Modification: N-glycosylated.
Cellular Location: Cell membrane.

Images
Western Blot - Anti-BTN3A1 Antibody from ABclonal (A10288) - Antibody Supply Service
Western blot analysis of extract of various cells, using BTN3A1 antibody.

Product Code - A10288
Size Price Quantity
50µl £148
100µl £243
200µl £372

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