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Anti-SNX17 Antibody

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ABclonal
A10274
Overview
Name: Anti-SNX17 Antibody
Description: Rabbit polyclonal antibody to SNX17.
Applications: WB
Dilutions: WB 1:1000 - 1:2000
Reactivity: Human
Immunogen: Recombinant protein of human SNX17
Protein Length: 470
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at -20℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: Critical regulator of endosomal recycling of numerous receptors, channels, and other transmembrane proteins. Binds to NPxY sequences in the cytoplasmic tails of target cargos. Plays a role in the sorting of endocytosed LRP1 and APP, and prevents their degradation. Required for maintenance of normal cell surface levels of APP and LRP1. Recycles internalized integrins ITGB1, ITGB5 and their associated alpha subunits, preventing them from lysosomal degradation. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)).
Sequence Similarities: Belongs to the sorting nexin family.
Cellular Location: Cytoplasm. Early endosome. Cytoplasmic vesicle membrane.
UniProt: Q15036
Gene ID: 9784
Synonyms: Similar to a putative C elegans gene encoded in cosmid F17H10 Antibody
Sorting nexin 17 Antibody

Images
Western Blot - Anti-SNX17 Antibody from ABclonal (A10274) - Antibody Supply Service
Western blot analysis of extract of A549 cells, using SNX17 antibody.

Product Code - A10274
Size Price Quantity
50µl £148
100µl £243
200µl £372

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