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Anti-NMI Antibody

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ABclonal
A10265
Details
Description: Rabbit polyclonal antibody to NMI.
Category: Primary Antibodies
Applications: WB
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Reactivity: Human
UniProt: Q13287
Gene ID: 9111
Immunogen: Recombinant protein of human NMI
Protein Length: 307
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification: Affinity purification
Background: NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias.
Storage: Store at -20℃. Avoid freeze / thaw cycles.
Recommended Dilutions: WB 1:500 - 1:2000

Target (Information from UniProt)
Function: May be involved in augmenting coactivator protein recruitment to a group of sequence-specific transcription factors. Augments cytokine-mediated STAT transcription. Enhances CBP/p300 coactivator protein recruitment to STAT1 and STAT5.
Tissue Specificity: Expressed in all adult and fetal tissues except brain and skin. More abundant in fetal tissues especially liver.
Sequence Similarities: Belongs to the NMI family.
Cellular Location: Cytoplasm.

Images
Western Blot - Anti-NMI Antibody from ABclonal (A10265) - Antibody Supply Service
Western blot analysis of extract of various cells, using NMI antibody.

Product Code - A10265
Size Price Quantity
50µl £148
100µl £243
200µl £372

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