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Anti-CDK13 Antibody

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Name: Anti-CDK13 Antibody
Description: Rabbit polyclonal antibody to CDK13.
Applications: WB
Dilutions: WB 1:1000 - 1:2000
Reactivity: Human
Immunogen: Recombinant protein of human CDK13
Protein Length: 1512
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at -20℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: Cyclin-dependent kinase which displays CTD kinase activity and is required for RNA splicing. Has CTD kinase activity by hyperphosphorylating the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit RPB1, thereby acting as a key regulator of transcription elongation. Required for RNA splicing, probably by phosphorylating SRSF1/SF2. Required during hematopoiesis. In case of infection by HIV-1 virus, interacts with HIV-1 Tat protein acetylated at 'Lys-50' and 'Lys-51', thereby increasing HIV-1 mRNA splicing and promoting the production of the doubly spliced HIV-1 protein Nef.
Tissue Specificity: Expressed in fetal brain, liver, muscle and in adult brain. Also expressed in neuroblastoma and glioblastoma tumors.
Sequence Similarities: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Cellular Location: Nucleus speckle.
UniProt: Q14004
Gene ID: 8621
Synonyms: CDC2 related protein kinase 5 Antibody
CDC2-related protein kinase 5 Antibody
CDC2L Antibody
CDC2L5 Antibody
CDK13_HUMAN Antibody
cell division controller cholinesterase related Antibody
cell division cycle 2 like 5 Antibody
cell division cycle 2 like 5 (cholinesterase related cell division controller) Antibody
Cell division cycle 2 like protein kinase 5 Antibody
Cell division cycle 2-like protein kinase 5 Antibody
Cell division protein kinase 13 Antibody
CHED Antibody
Cholinesterase related cell division controller Antibody
Cholinesterase-related cell division controller Antibody
cyclin dependent kinase 13 Antibody
Cyclin-dependent kinase 13 Antibody
hCDK13 Antibody

Western Blot - Anti-CDK13 Antibody from ABclonal (A10258) - Antibody Supply Service
Western blot analysis of extract of various cells, using CDK13 antibody.

Product Code - A10258
Size Price Quantity
50µl £148
100µl £243
200µl £372

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