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Anti-TIAM1 Antibody

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ABclonal
A10252
Overview
Name: Anti-TIAM1 Antibody
Description: Rabbit polyclonal antibody to TIAM1.
Applications: WB
Dilutions: WB 1:200 - 1:2000
Reactivity: Human
Immunogen: Recombinant protein of human TIAM1
Protein Length: 1591
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at -20℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA. Required for normal cell adhesion and cell migration.
Tissue Specificity: Found in virtually all analyzed tumor cell lines including B- and T-lymphomas, neuroblastomas, melanomas and carcinomas.
Sequence Similarities: Belongs to the TIAM family.
Cellular Location: Cell junction. Cell membrane.

Detected at the boundary between cells with actin-rich protrusions (By similarity). Presence of KRIT1, CDH5 and RAP1B is required for its localization to the cell junction.
UniProt: Q13009
Gene ID: 7074
Synonyms: Human T-lymphoma invasion and metastasis inducing TIAM1 protein Antibody
T cell lymphoma invasion and metastasis 1 Antibody
T lymphoma invasion and metastasis inducing TIAM1 protein Antibody
T-lymphoma invasion and metastasis-inducing protein 1 Antibody
TIAM-1 Antibody
TIAM1_HUMAN Antibody

Images
Western Blot - Anti-TIAM1 Antibody from ABclonal (A10252) - Antibody Supply Service
Western blot analysis of extract of various cells, using TIAM1 antibody.

Product Code - A10252
Size Price Quantity
50µl £148
100µl £243
200µl £372

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