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Anti-MMP1 Antibody

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ABclonal
A10168
Details
Description: Rabbit polyclonal antibody to MMP1.
Category: Primary Antibodies
Applications: WB, IHC, ICC
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Reactivity: Human
UniProt: P03956
Gene ID: 4312
Immunogen: A synthetic peptide of human MMP1
Protein Length: 469
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles.
Recommended Dilutions: WB 1:500 - 1:2000, IHC 1:50 - 1:200, ICC 1:50 - 1:200

Target (Information from UniProt)
Function: Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X (PubMed:2557822, PubMed:2153297, PubMed:1645757). In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated neurotoxicity (PubMed:16807369).
Sequence Similarities: Belongs to the peptidase M10A family.
Post-Translational Modification: Undergoes autolytic cleavage to two major forms (22 kDa and 27 kDa). A minor form (25 kDa) is the glycosylated form of the 22 kDa form. The 27 kDa form has no activity while the 22/25 kDa form can act as activator for collagenase.
Cellular Location: Secreted > Extracellular space > Extracellular matrix.

Images
Western Blot - Anti-MMP1 Antibody from ABclonal (A10168) - Antibody Supply Service
Western blot analysis of extracts of various cells, using MMP1 antibody.

Product Code - A10168
Size Price Quantity
100µl £307
200µl £452

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