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Anti-SEMA4D Antibody

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ABclonal
A10136
Overview
Name: Anti-SEMA4D Antibody
Description: Rabbit polyclonal antibody to SEMA4D.
Applications: WB
Dilutions: WB 1:200 - 1:1000
Reactivity: Human
Immunogen: Recombinant protein of human SEMA4D
Protein Length: 862
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at -20℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro). Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA.
Tissue Specificity: Strongly expressed in skeletal muscle, peripheral blood lymphocytes, spleen, and thymus and also expressed at lower levels in testes, brain, kidney, small intestine, prostate, heart, placenta, lung and pancreas, but not in colon and liver.
Sequence Similarities: Belongs to the semaphorin family.
Cellular Location: Cell membrane.
UniProt: Q92854
Gene ID: 10507
Synonyms: A8 Antibody
BB 18 Antibody
BB18 Antibody
CD 100 Antibody
CD100 Antibody
CD100 antigen Antibody
Coll 4 Antibody
COLL4 Antibody
Collapsin 4 Antibody
Collapsin4 Antibody
GR3 Antibody
Leukocyte activation antigen CD100 Antibody
M sema G Antibody
MSEMA Antibody
SEM4D_HUMAN Antibody
Sema 4d Antibody
Sema domain immunoglobulin domain Ig transmembrane domain TM and short cytoplasmic domain semaphorin 4D Antibody
Sema H Antibody
SEMA J Antibody
Semacl 2 Antibody
Semacl2 Antibody
SemaH Antibody
SEMAJ Antibody
Semaphorin 4D Antibody
Semaphorin C like 2 Antibody
Semaphorin H Antibody
Semaphorin J Antibody
Semaphorin-4D Antibody
Semaphorin4D Antibody
SemaphorinJ Antibody
Semcl 2 Antibody
Semcl2 Antibody

Images
Western Blot - Anti-SEMA4D Antibody from ABclonal (A10136) - Antibody Supply Service
Western blot analysis of extracts of 293T cells, using SEMA4D antibody.

Product Code - A10136
Size Price Quantity
50µl £148
100µl £243
200µl £372

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