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Anti-TRIB1 Antibody

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ABclonal
A10134
Overview
Name: Anti-TRIB1 Antibody
Description: Rabbit polyclonal antibody to TRIB1.
Applications: WB
Dilutions: WB 1:1000 - 1:4000
Reactivity: Human
Immunogen: Recombinant protein of human TRIB1
Protein Length: 372
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at -20℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: Adapter protein involved in protein degradation by interacting with RFWD2/COP1 ubiquitin ligase (PubMed:27041596). The RFWD2-binding motif is masked by autoinhibitory interactions with the protein kinase domain (PubMed:26455797). Serves to alter RFWD2 substrate specificity by directing the activity of RFWD2 toward CEBPA (PubMed:27041596). Binds selectively the recognition sequence of CEBPA (PubMed:26455797). Regulates myeloid cell differentiation by altering the expression of CEBPA in a RFWD2-dependent manner (By similarity). Controls macrophage, eosinophil and neutrophil differentiation via the COP1-binding domain (By similarity). Interacts with MAPK kinases and regulates activation of MAP kinases, but has no kinase activity (PubMed:15299019, PubMed:26455797).
Tissue Specificity: Expressed in most human tissues with the highest levels in skeletal muscle, thyroid gland, pancreas, peripheral blood leukocytes, and bone marrow.
Sequence Similarities: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. Tribbles subfamily.
UniProt: Q96RU8
Gene ID: 10221
Synonyms: C8FW Antibody
G-protein-coupled receptor-induced gene 2 protein Antibody
GIG-2 Antibody
GIG2 Antibody
SKIP1 Antibody
TRB-1 Antibody
TRB1 Antibody
TRIB1_HUMAN Antibody
Tribbles homolog 1 Antibody

Images
Western Blot - Anti-TRIB1 Antibody from ABclonal (A10134) - Antibody Supply Service
Western blot analysis of extracts of various cells, using TRIB1 antibody.

Product Code - A10134
Size Price Quantity
50µl £148
100µl £243
200µl £372

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