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Anti-CIR1 Antibody

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Description: Rabbit polyclonal antibody to CIR1.
Category: Primary Antibodies
Applications: WB
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Reactivity: Human
UniProt: Q86X95
Gene ID: 9541
Immunogen: Recombinant protein of human CIR1
Protein Length: 450
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles.
Recommended Dilutions: WB 1:500 - 1:2000

Target (Information from UniProt)
Function: May modulate splice site selection during alternative splicing of pre-mRNAs (By similarity). Regulates transcription and acts as corepressor for RBPJ. Recruits RBPJ to the Sin3-histone deacetylase complex (HDAC). Required for RBPJ-mediated repression of transcription.
Tissue Specificity: Highly expressed in heart, brain, placenta, liver, skeletal muscle and pancreas.
Post-Translational Modification: Phosphorylated by NEK6.
Cellular Location: Nucleus speckle. Cytoplasm > Cytoskeleton > Microtubule organizing center > Centrosome.

Colocalizes with NEK6 in the centrosome.

Western Blot - Anti-CIR1 Antibody from ABclonal (A10133) - Antibody Supply Service
Western blot analysis of extracts of U2OS cells, using CIR1 antibody.

Product Code - A10133
Size Price Quantity
50µl £148
100µl £243
200µl £372

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