|Description:||Rabbit polyclonal antibody to KEL.|
|Immunogen:||Recombinant protein of human KEL|
|Formulation:||PBS with 0.02% sodium azide, 50% glycerol, pH7.3.|
|Storage:||Store at -20℃. Avoid freeze / thaw cycles.|
|Recommended Dilutions:||WB 1:200 - 1:1000|
Target (Information from UniProt)
|Function:||Zinc endopeptidase with endothelin-3-converting enzyme activity. Cleaves EDN1, EDN2 and EDN3, with a marked preference for EDN3.|
|Tissue Specificity:||Expressed at high levels in erythrocytes and testis (in Sertoli cells), and, at lower levels, in skeletal muscle, tonsils (in follicular dendritic cells), lymph node, spleen and appendix (at protein level). Also expressed in many adult and fetal nonerythroid tissues, including brain, spleen, lymph nodes and bone marrow.|
|Sequence Similarities:||Belongs to the peptidase M13 family.|
|Cellular Location:||Cell membrane.
Spans the erythrocyte membrane, and is attached to the underlying cytoskeleton.
Western blot analysis of extracts of various cells, using KEL antibody.