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Anti-ATP2A1 Antibody

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Description: Rabbit polyclonal antibody to ATP2A1.
Category: Primary Antibodies
Applications: WB
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Reactivity: Human
UniProt: O14983
Gene ID: 487
Immunogen: Recombinant protein of human ATP2A1
Protein Length: 1001
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles.
Recommended Dilutions: WB 1:200 - 1:1000

Target (Information from UniProt)
Function: Key regulator of striated muscle performance by acting as the major Ca(2+) ATPase responsible for the reuptake of cytosolic Ca(2+) into the sarcoplasmic reticulum. Catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction.
Tissue Specificity: Skeletal muscle, fast twitch muscle (type II) fibers.
Involvement in Disease: Brody myopathy: A disorder of muscle function that is characterized by painless muscle cramping and exercise-induced impairment of muscle relaxation.
Sequence Similarities: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
Cellular Location: Endoplasmic reticulum membrane. Sarcoplasmic reticulum membrane.

Western Blot - Anti-ATP2A1 Antibody from ABclonal (A10104) - Antibody Supply Service
Western blot analysis of extracts of HL-60 cells, using ATP2A1 antibody.

Product Code - A10104
Size Price Quantity
50µl £148
100µl £243
200µl £372

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