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Anti-INF2 Antibody

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ABclonal
A10038
Overview
Name: Anti-INF2 Antibody
Description: Rabbit polyclonal antibody to INF2.
Applications: WB
Dilutions: WB 1:500 - 1:1000
Reactivity: Human
Immunogen: Recombinant protein of human INF2
Protein Length: 1249 (234)
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at -20℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: Severs actin filaments and accelerates their polymerization and depolymerization.
Tissue Specificity: Widely expressed. In the kidney, expression is apparent in podocytes and some tubule cells.
Involvement in Disease: Focal segmental glomerulosclerosis 5: A renal pathology defined by the presence of segmental sclerosis in glomeruli and resulting in proteinuria, reduced glomerular filtration rate and progressive decline in renal function. Renal insufficiency often progresses to end-stage renal disease, a highly morbid state requiring either dialysis therapy or kidney transplantation.

Charcot-Marie-Tooth disease, dominant, intermediate type, E: A form of Charcot-Marie-Tooth disease, a disorder of the peripheral nervous system, characterized by progressive weakness and atrophy, initially of the peroneal muscles and later of the distal muscles of the arms. The dominant intermediate type E is characterized by clinical and pathologic features intermediate between demyelinating and axonal peripheral neuropathies, and motor median nerve conduction velocities ranging from 25 to 45 m/sec. Patients additionally manifest focal segmental glomerulonephritis, proteinuria, progression to end-stage renal disease, and a characteristic histologic pattern on renal biopsy.
Sequence Similarities: Belongs to the formin homology family.
Cellular Location: Cytoplasm > Perinuclear region.
UniProt: Q27J81
Gene ID: 64423
Synonyms: C14orf151 Antibody
C14orf173 Antibody
CMTDIE Antibody
DKFZp762A0214 Antibody
FLJ22056 Antibody
FSGS5 Antibody
HBEAG binding protein 2 binding protein C Antibody
HBEBP2 binding protein C Antibody
HBEBP2-binding protein C Antibody
INF 2 Antibody
INF2_HUMAN Antibody
Inverted formin 2 Antibody
Inverted formin FH2 and WH2 domain containing Antibody
Inverted formin-2 Antibody
MGC13251 Antibody
pp9484 Antibody

Images
Western Blot - Anti-INF2 Antibody from ABclonal (A10038) - Antibody Supply Service
Western blot analysis of extracts of various cells, using INF2 antibody.

Product Code - A10038
Size Price Quantity
50µl £148
100µl £243
200µl £372

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