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Anti-NOSIP Antibody

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ABclonal
A10024
Overview
Name: Anti-NOSIP Antibody
Description: Rabbit polyclonal antibody to NOSIP.
Applications: WB
Dilutions: WB 1:500 - 1:2000
Reactivity: Human
Immunogen: Recombinant protein of human NOSIP
Protein Length: 301
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Purification: Affinity purification
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at -20℃. Avoid freeze / thaw cycles.

Target (Information from UniProt)
Function: E3 ubiquitin-protein ligase that is essential for proper development of the forebrain, the eye, and the face. Catalyzes monoubiquitination of serine/threonine-protein phosphatase 2A (PP2A) catalytic subunit PPP2CA/PPP2CB (By similarity). Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity (PubMed:11149895, PubMed:15548660, PubMed:16135813).
Tissue Specificity: Expressed in heart, brain and lung. Present in endothelial cells (at protein level).
Sequence Similarities: Belongs to the NOSIP family.
Cellular Location: Cytoplasm. Nucleus.

Translocates from nucleus to cytoplasm in the G2 phase of the cell cycle (PubMed:16135813).
UniProt: Q9Y314
Gene ID: 51070
Synonyms: CGI 25 Antibody
CGI25 Antibody
CGI25 protein Antibody
eNOS interacting protein Antibody
Nitric oxide synthase interacting protein Antibody

Images
Western Blot - Anti-NOSIP Antibody from ABclonal (A10024) - Antibody Supply Service
Western blot analysis of extracts of various cells, using NOSIP antibody.

Product Code - A10024
Size Price Quantity
50µl £148
100µl £243
200µl £372

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